IQGAP1 Functions as a Modulator of Dishevelled Nuclear Localization in Wnt Signaling

Dishevelled (DVL) is a central factor in the Wnt signaling pathway, which is highly conserved among various organisms. DVL plays important roles in transcriptional activation in the nucleus, but the molecular mechanisms underlying their nuclear localization remain unclear. In the present study, we i...

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Bibliographic Details
Main Authors: Goto, Toshiyasu, Sato, Atsushi, Shimizu, Masahiro, Adachi, Shungo, Satoh, Kiyotoshi, Iemura, Shun-ichiro, Natsume, Tohru, Shibuya, Hiroshi
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618174/