HPV16 E7 Protein and hTERT Proteins Defective for Telomere Maintenance Cooperate to Immortalize Human Keratinocytes

Previous studies have shown that wild-type human telomerase reverse transcriptase (hTERT) protein can functionally replace the human papillomavirus type 16 (HPV-16) E6 protein, which cooperates with the viral E7 protein in the immortalization of primary keratinocytes. In the current study, we made t...

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Bibliographic Details
Main Authors: Miller, Jonathan, Dakic, Aleksandra, Chen, Renxiang, Palechor-Ceron, Nancy, Dai, Yuhai, Kallakury, Bhaskar, Schlegel, Richard, Liu, Xuefeng
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617164/