Genome-wide copy number profiling of single cells in S-phase reveals DNA-replication domains

Single-cell genomics is revolutionizing basic genome research and clinical genetic diagnosis. However, none of the current research or clinical methods for single-cell analysis distinguishes between the analysis of a cell in G1-, S- or G2/M-phase of the cell cycle. Here, we demonstrate by means of a...

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Bibliographic Details
Main Authors: Van der Aa, Niels, Cheng, Jiqiu, Mateiu, Ligia, Esteki, Masoud Zamani, Kumar, Parveen, Dimitriadou, Eftychia, Vanneste, Evelyne, Moreau, Yves, Vermeesch, Joris Robert, Voet, Thierry
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616740/