Epigenetic therapy: use of agents targeting deacetylation and methylation in cancer management

The emergence of epigenetic mechanisms as key regulators of gene expression has led to dramatic advances in understanding cancer biology. Driven by complex layers that include aberrant DNA methylation and histone modification, epigenetic aberrations have emerged as critical processes that disrupt ce...

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Bibliographic Details
Main Authors: Ho, Allen S, Turcan, Sevin, Chan, Timothy A
Format: Online
Language:English
Published: Dove Medical Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615839/