Transforming Growth Factor-β1 and Laminin-111 Cooperate in the Regulation of Expression of Interleukin-6 and Interleukin-8 in Synovial Fibroblasts
In a recent study we showed that binding of synovial fibroblasts (SF) to laminin-111 (LM-111) in the presence of TGF-β1 induced a significant production of IL-16. Here we go on to investigate the regulation of IL-6 and IL-8 in SF by LM-111 and TGF-β1. Changes in steady state mRNA levels encoding the...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Master Publishing Group
2010
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615287/ |