Applying Mathematical Tools to Accelerate Vaccine Development: Modeling Shigella Immune Dynamics

We establish a mathematical framework for studying immune interactions with Shigella, a bacteria that kills over one million people worldwide every year. The long-term goal of this novel approach is to inform Shigella vaccine design by elucidating which immune components and bacterial targets are cr...

Full description

Bibliographic Details
Main Authors: Davis, Courtney L., Wahid, Rezwanul, Toapanta, Franklin R., Simon, Jakub K., Sztein, Marcelo B., Levy, Doron
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614931/