Neutralization of IL-4 and IFN-γ Facilitates inducing TGF-β-induced CD4+Foxp3+ Regulatory Cells
It has been well recognized that TGF-β is able to induce CD4+CD25+Foxp3+ suppressor/regulatory T (iTreg) cells and IL-2 facilitates iTreg induction and expansion, however, only half of TGF-β-induced CD4+CD25+ cells express Foxp3 and remaining CD4+CD25+Foxp3- cells may represent effector cells. Wheth...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Master Publishing Group
2008
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614670/ |