Assessing the Radiation Response of Lung Cancer with Different Gene Mutations Using Genetically Engineered Mice

Purpose: Non-small cell lung cancers (NSCLC) are a heterogeneous group of carcinomas harboring a variety of different gene mutations. We have utilized two distinct genetically engineered mouse models of human NSCLC (adenocarcinoma) to investigate how genetic factors within tumor parenchymal cells in...

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Main Authors:	Perez, Bradford A., Ghafoori, A. Paiman, Lee, Chang-Lung, Johnston, Samuel M., Li, Yifan, Moroshek, Jacob G., Ma, Yan, Mukherjee, Sayan, Kim, Yongbaek, Badea, Cristian T., Kirsch, David G.
Format:	Online
Language:	English
Published:	Frontiers Media S.A. 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613757/

id	pubmed-3613757
recordtype	oai_dc
spelling	pubmed-36137572013-04-05 Assessing the Radiation Response of Lung Cancer with Different Gene Mutations Using Genetically Engineered Mice Perez, Bradford A. Ghafoori, A. Paiman Lee, Chang-Lung Johnston, Samuel M. Li, Yifan Moroshek, Jacob G. Ma, Yan Mukherjee, Sayan Kim, Yongbaek Badea, Cristian T. Kirsch, David G. Oncology Purpose: Non-small cell lung cancers (NSCLC) are a heterogeneous group of carcinomas harboring a variety of different gene mutations. We have utilized two distinct genetically engineered mouse models of human NSCLC (adenocarcinoma) to investigate how genetic factors within tumor parenchymal cells influence the in vivo tumor growth delay after one or two fractions of radiation therapy (RT). Frontiers Media S.A. 2013-04-02 /pmc/articles/PMC3613757/ /pubmed/23565506 http://dx.doi.org/10.3389/fonc.2013.00072 Text en Copyright © 2013 Perez, Ghafoori, Lee, Johnston, Li, Moroshek, Ma, Mukherjee, Kim, Badea and Kirsch. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Perez, Bradford A. Ghafoori, A. Paiman Lee, Chang-Lung Johnston, Samuel M. Li, Yifan Moroshek, Jacob G. Ma, Yan Mukherjee, Sayan Kim, Yongbaek Badea, Cristian T. Kirsch, David G.
spellingShingle	Perez, Bradford A. Ghafoori, A. Paiman Lee, Chang-Lung Johnston, Samuel M. Li, Yifan Moroshek, Jacob G. Ma, Yan Mukherjee, Sayan Kim, Yongbaek Badea, Cristian T. Kirsch, David G. Assessing the Radiation Response of Lung Cancer with Different Gene Mutations Using Genetically Engineered Mice
author_facet	Perez, Bradford A. Ghafoori, A. Paiman Lee, Chang-Lung Johnston, Samuel M. Li, Yifan Moroshek, Jacob G. Ma, Yan Mukherjee, Sayan Kim, Yongbaek Badea, Cristian T. Kirsch, David G.
author_sort	Perez, Bradford A.
title	Assessing the Radiation Response of Lung Cancer with Different Gene Mutations Using Genetically Engineered Mice
title_short	Assessing the Radiation Response of Lung Cancer with Different Gene Mutations Using Genetically Engineered Mice
title_full	Assessing the Radiation Response of Lung Cancer with Different Gene Mutations Using Genetically Engineered Mice
title_fullStr	Assessing the Radiation Response of Lung Cancer with Different Gene Mutations Using Genetically Engineered Mice
title_full_unstemmed	Assessing the Radiation Response of Lung Cancer with Different Gene Mutations Using Genetically Engineered Mice
title_sort	assessing the radiation response of lung cancer with different gene mutations using genetically engineered mice
description	Purpose: Non-small cell lung cancers (NSCLC) are a heterogeneous group of carcinomas harboring a variety of different gene mutations. We have utilized two distinct genetically engineered mouse models of human NSCLC (adenocarcinoma) to investigate how genetic factors within tumor parenchymal cells influence the in vivo tumor growth delay after one or two fractions of radiation therapy (RT).
publisher	Frontiers Media S.A.
publishDate	2013
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613757/
_version_	1611966723951427584

Assessing the Radiation Response of Lung Cancer with Different Gene Mutations Using Genetically Engineered Mice

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