Get3 is a holdase chaperone and moves to deposition sites for aggregated proteins when membrane targeting is blocked
The endomembrane system of yeast contains different tail-anchored proteins that are post-translationally targeted to membranes via their C-terminal transmembrane domain. This hydrophobic segment could be hazardous in the cytosol if membrane insertion fails, resulting in the need for energy-dependent...
| Main Authors: | , , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Company of Biologists
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613179/ |