Genotyping of CYP2C9 and VKORC1 in the Arabic Population of Al-Ahsa, Saudi Arabia

Polymorphisms in the genes encoding CYP2C9 enzyme and VKORC1 reductase significantly influence the dose variability of coumarinic oral anticoagulants (COAs). Substantial inter- and intraethnic variability exists in the frequencies of CYP2C9 ∗2 and ∗3 and VKORC1 –1639A alleles. However, the prevalenc...

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Bibliographic Details
Main Authors: Alzahrani, Abdullah M., Ragia, Georgia, Hanieh, Hamza, Manolopoulos, Vangelis G.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613048/