Genotyping of CYP2C9 and VKORC1 in the Arabic Population of Al-Ahsa, Saudi Arabia
Polymorphisms in the genes encoding CYP2C9 enzyme and VKORC1 reductase significantly influence the dose variability of coumarinic oral anticoagulants (COAs). Substantial inter- and intraethnic variability exists in the frequencies of CYP2C9 ∗2 and ∗3 and VKORC1 –1639A alleles. However, the prevalenc...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613048/ |