Frequent Engagement of RelB Activation Is Critical for Cell Survival in Multiple Myeloma

The NF-κB family of transcription factors has emerged as a key player in the pathogenesis of multiple myeloma (MM). NF-κB is activated by at least two major signaling pathways. The classical pathway results in the activation of mainly RelA containing dimers, whereas the alternative pathway leads to...

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Bibliographic Details
Main Authors: Cormier, Françoise, Monjanel, Hélène, Fabre, Claire, Billot, Katy, Sapharikas, Elène, Chereau, Fanny, Bordereaux, Didier, Molina, Thierry J., Avet-Loiseau, Hervé, Baud, Véronique
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610937/