Genetic Diversity and Lack of Artemisinin Selection Signature on the Plasmodium falciparum ATP6 in the Greater Mekong Subregion

Genetic Diversity and Lack of Artemisinin Selection Signature on the Plasmodium falciparum ATP6 in the Greater Mekong Subregion

The recent detection of clinical Artemisinin (ART) resistance manifested as delayed parasite clearance in the Cambodia-Thailand border area raises a serious concern. The mechanism of ART resistance is not clear; but the P. falciparum sarco/endoplasmic reticulum Ca2+-ATPase (PfSERCA or PfATP6) has be...

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Bibliographic Details
Main Authors: Miao, Miao, Wang, Zenglei, Yang, Zhaoqing, Yuan, Lili, Parker, Daniel M., Putaporntip, Chaturong, Jongwutiwes, Somchai, Xangsayarath, Phonepadith, Pongvongsa, Tiengkham, Moji, Hazuhiko, Dinh Tuong, Trinh, Abe, Tomoko, Nakazawa, Shusuke, Kyaw, Myat Phone, Yan, Guiyun, Sirichaisinthop, Jeeraphat, Sattabongkot, Jetsumon, Mu, Jianbing, Su, Xin-zhuan, Kaneko, Osamu, Cui, Liwang
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608609/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608609/

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