RET Gene Abnormalities and Thyroid Disease: Who Should be Screened and When

Mutations in the RET proto-oncogene have been implicated in the pathogenesis of several forms of medullary thyroid cancer (MTC). Multiple endocrine neoplasia type 2 (MEN-2) is an autosomal dominant syndrome caused by germline activating mutations of the RET proto-oncogene and has been categorized in...

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Bibliographic Details
Main Authors: Salehian, Behrouz, Samoa, Raynald
Format: Online
Language:English
Published: Galenos Publishing 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608003/