Construction and validation of a homology model of the human voltage-gated proton channel hHV1

The topological similarity of voltage-gated proton channels (HV1s) to the voltage-sensing domain (VSD) of other voltage-gated ion channels raises the central question of whether HV1s have a similar structure. We present the construction and validation of a homology model of the human HV1 (hHV1). Mul...

Full description

Bibliographic Details
Main Authors: Kulleperuma, Kethika, Smith, Susan M.E., Morgan, Deri, Musset, Boris, Holyoake, John, Chakrabarti, Nilmadhab, Cherny, Vladimir V., DeCoursey, Thomas E., Pomès, Régis
Format: Online
Language:English
Published: The Rockefeller University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607825/