Specificity and Function of Archaeal DNA Replication Initiator Proteins

Chromosomes with multiple DNA replication origins are a hallmark of Eukaryotes and some Archaea. All eukaryal nuclear replication origins are defined by the origin recognition complex (ORC) that recruits the replicative helicase MCM(2-7) via Cdc6 and Cdt1. We find that the three origins in the singl...

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Bibliographic Details
Main Authors: Samson, Rachel Y., Xu, Yanqun, Gadelha, Catarina, Stone, Todd A., Faqiri, Jamal N., Li, Dongfang, Qin, Nan, Pu, Fei, Liang, Yun Xiang, She, Qunxin, Bell, Stephen D.
Format: Online
Language:English
Published: Cell Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607249/