Characterization of Protective Immune Responses Induced by Pneumococcal Surface Protein A in Fusion with Pneumolysin Derivatives

Pneumococcal surface protein A (PspA) and Pneumolysin derivatives (Pds) are important vaccine candidates, which can confer protection in different models of pneumococcal infection. Furthermore, the combination of these two proteins was able to increase protection against pneumococcal sepsis in mice....

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Bibliographic Details
Main Authors: Goulart, Cibelly, da Silva, Thais Raquel, Rodriguez, Dunia, Politano, Walter Rodrigo, Leite, Luciana C. C., Darrieux, Michelle
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606166/