Chromosome Segregation: Disarming the Protector
One of the key features of meiosis is that shugoshin in complex with protein phosphatase 2A (PP2A) protects centromeric cohesin during meiosis I, but not during meiosis II. A new model suggests that a PP2A inhibitor mediates deprotection of centromeric cohesin during meiosis II.
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Cell Press
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605575/ |