DNA Synthesis Is Required for Reprogramming Mediated by Stem Cell Fusion

Embryonic stem cells (ESCs) can instruct the conversion of differentiated cells toward pluripotency following cell-to-cell fusion by a mechanism that is rapid but poorly understood. Here, we used centrifugal elutriation to enrich for mouse ESCs at sequential stages of the cell cycle and showed that...

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Bibliographic Details
Main Authors: Tsubouchi, Tomomi, Soza-Ried, Jorge, Brown, Karen, Piccolo, Francesco M., Cantone, Irene, Landeira, David, Bagci, Hakan, Hochegger, Helfrid, Merkenschlager, Matthias, Fisher, Amanda G.
Format: Online
Language:English
Published: Cell Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605571/