Mice deficient in Epg5 exhibit selective neuronal vulnerability to degeneration

Cortical layer 5 pyramidal neurons and spinal cord motor neurons are selectively vulnerable to degeneration after loss of the autophagy gene Epg5.

Bibliographic Details
Main Authors: Zhao, Hongyu, Zhao, Yan G., Wang, Xingwei, Xu, Lanjun, Miao, Lin, Feng, Du, Chen, Quan, Kovács, Attila L., Fan, Dongsheng, Zhang, Hong
Format: Online
Language:English
Published: The Rockefeller University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601354/