Vps35 loss promotes hyperresorptive osteoclastogenesis and osteoporosis via sustained RANKL signaling
Vps35 deficiency leads to impaired RANK trafficking, enhanced RANKL signaling, increased osteoclastogenesis and function, and osteoporotic deficits.
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601351/ |