Depletion of T lymphocytes is correlated with response to temozolomide in melanoma patients

Therapeutic strategies to deplete lymphocytes, especially regulatory T cells, in cancer patients have been proposed to increase the benefits of (immuno)chemotherapy. In this study, we explored the influence of temozolomide (TMZ) on different T-cell populations and addressed if the depletion of CD4+...

Full description

Bibliographic Details
Main Authors: Iversen, Trine Zeeberg, Brimnes, Marie Klinge, Nikolajsen, Kirsten, Andersen, Rikke Sick, Hadrup, Sine Reker, Andersen, Mads Hald, Bastholt, Lars, Svane, Inge Marie
Format: Online
Language:English
Published: Landes Bioscience 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601183/