Hepatoma polarization limits CD81 and hepatitis C virus dynamics

Many viruses target the polarized epithelial apex during host invasion. In contrast, hepatitis C virus (HCV) engages receptors at the basal surface of hepatocytes in the polarized liver parenchyma. Hepatocyte polarization limits HCV entry by undefined mechanism(s). Given the recent reports highlight...

Full description

Bibliographic Details
Main Authors: Harris, H J, Clerte, C, Farquhar, M J, Goodall, M, Hu, K, Rassam, P, Dosset, P, Wilson, G K, Balfe, P, IJzendoorn, S C, Milhiet, P E, McKeating, J A
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599488/