Structural insights into RISC assembly facilitated by dsRNA-binding domains of human RNA helicase A (DHX9)
Intensive research interest has focused on small RNA-processing machinery and the RNA-induced silencing complex (RISC), key cellular machines in RNAi pathways. However, the structural mechanism regarding RISC assembly, the primary step linking small RNA processing and RNA-mediated gene silencing, is...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597700/ |