Quantitative FRET Imaging to Visualize the Invasiveness of Live Breast Cancer Cells

Matrix metalloproteinases (MMPs) remodel tumor microenvironment and promote cancer metastasis. Among the MMP family proteases, the proteolytic activity of the pro-tumorigenic and pro-metastatic membrane-type 1 (MT1)-MMP constitutes a promising and targetable biomarker of aggressive cancer tumors. In...

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Bibliographic Details
Main Authors: Lu, Shaoying, Wang, Yi, Huang, He, Pan, Yijia, Chaney, Eric J., Boppart, Stephen A., Ozer, Howard, Strongin, Alex Y., Wang, Yingxiao
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596289/