Bromocriptine enhances the uptake of 99mTc-MIBI in patients with hepatocellular carcinoma

99mTc-methoxyisobutyl isonitrile (MIBI) is a suitable transport substrate for the multidrug resistance gene product P-glycoprotein (P-gp) and widely used for tumor imaging. Bromocriptine has been shown to inhibit the ATPase activity and the function of P-gp. We hypothesized that bromocriptine could...

Full description

Bibliographic Details
Main Authors: Chai, Xiangting, Liu, Qiaoyu, Shao, Wenyu, Zhang, Feng, Wang, Xuehao, Wang, Hai
Format: Online
Language:English
Published: Editorial Department of Journal of Biomedical Research 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596066/