β-Lapachone, a substrate of NAD(P)H:quinone oxidoreductase, induces anti-inflammatory heme oxygenase-1 via AMP-activated protein kinase activation in RAW264.7 macrophages

β-Lapachone, a substrate of NAD(P)H:quinone oxidoreductase, induces anti-inflammatory heme oxygenase-1 via AMP-activated protein kinase activation in RAW264.7 macrophages

AMP-activated protein kinase (AMPK), a crucial regulator of energy metabolic homeostasis, is suggested to regulate inflammatory responses, but its precise mechanisms are not fully understood. It has been reported that pharmacological activation of AMPK induces heme oxygenase-1 (HO-1) expression. β-L...

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Bibliographic Details
Main Authors: Byun, Seung Jae, Son, Young, Hwan Cho, Baik, Chung, Hun-Taeg, Pae, Hyun-Ock
Format: Online
Language:English
Published: the Society for Free Radical Research Japan 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593126/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593126/

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