The impact of microcarrier culture optimization on the glycosylation profile of a monoclonal antibody

Microcarriers are widely used for the large-scale culture of attachment-dependent cells with increased cell densities and, ultimately, higher product yield. In these processes, the specific culture conditions can affect the quality of the product, which is closely related to its glycosylation patter...

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Bibliographic Details
Main Authors: Costa, Ana Rita, Withers, Joanne, Rodrigues, Maria Elisa, McLoughlin, Niaobh, Henriques, Mariana, Oliveira, Rosário, Rudd, Pauline M, Azeredo, Joana
Format: Online
Language:English
Published: Springer International Publishing AG 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592997/