Claudin-2 Expression Increases Tumorigenicity of Colon Cancer Cells: Role of Epidermal Growth Factor Receptor Activation

Claudin-2 is a unique member of the claudin family of transmembrane proteins as its expression is restricted to the leaky epithelium in vivo and correlates with epithelial leakiness in vitro. However, recent evidence suggests potential functions of claudin-2 that are relevant to neoplastic transform...

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Bibliographic Details
Main Authors: Dhawan, Punita, Ahmad, Rizwan, Chaturvedi, Rupesh, Smith, J. Joshua, Midha, Rajiv, Mittal, Mukul, Krishnan, Moorthy, Chen, Xi, Eschrich, Steven, Yeatman, Timothy J., Harris, Raymond C., Washington, M. Kay, Wilson, Keith T., Beauchamp, R. Daniel, Singh, Amar B.
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591522/