De novo modeling of the F420-reducing [NiFe]-hydrogenase from a methanogenic archaeon by cryo-electron microscopy

Methanogenic archaea use a [NiFe]-hydrogenase, Frh, for oxidation/reduction of F420, an important hydride carrier in the methanogenesis pathway from H2 and CO2. Frh accounts for about 1% of the cytoplasmic protein and forms a huge complex consisting of FrhABG heterotrimers with each a [NiFe] center,...

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Bibliographic Details
Main Authors: Mills, Deryck J, Vitt, Stella, Strauss, Mike, Shima, Seigo, Vonck, Janet
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591093/