A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy

During mammalian development, a subpopulation of endothelial cells in the cardinal vein (CV) expresses lymphatic-specific genes and subsequently develops into the first lymphatic structures, collectively termed as lymph sacs. Budding, sprouting and ballooning of lymphatic endothelial cells (LECs) ha...

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Bibliographic Details
Main Authors: Hägerling, René, Pollmann, Cathrin, Andreas, Martin, Schmidt, Christian, Nurmi, Harri, Adams, Ralf H, Alitalo, Kari, Andresen, Volker, Schulte-Merker, Stefan, Kiefer, Friedemann
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590982/