Unfolded Protein Response and Activated Degradative Pathways Regulation in GNE Myopathy

Although intracellular beta amyloid (Aβ) accumulation is known as an early upstream event in the degenerative course of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) myopathy, the process by which Aβdeposits initiate various degradative pathways, and their relationship have no...

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Bibliographic Details
Main Authors: Li, Honghao, Chen, Qi, Liu, Fuchen, Zhang, Xuemei, Li, Wei, Liu, Shuping, Zhao, Yuying, Gong, Yaoqin, Yan, Chuanzhu
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589370/