hTERT Extends the Life of Human Fibroblasts without Compromising Type I Interferon Signaling

Primary cells are often used to study viral replication and host-virus interactions as their antiviral pathways have not been altered or inactivated; however, their use is restricted by their short lifespan. Conventional methods to extend the life of primary cultures typically utilize viral oncogene...

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Bibliographic Details
Main Authors: Smith, Miles C., Goddard, Erica T., Perusina Lanfranca, Mirna, Davido, David J.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589264/