Evaluation of the Pharmacokinetic Interaction between Lesogaberan (AZD3355) and Esomeprazole in Healthy Subjects
Background: Transient lower esophageal sphincter relaxations (TLESRs) have been identified as a primary cause of reflux events in patients with gastroesophageal reflux disease (GERD). GABAB receptor agonists such as lesogaberan (AZD3355) have been shown to inhibit TLESRs in healthy subjects and pati...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Springer International Publishing
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586101/ |