The Novel Mas agonist, CGEN-856S, Attenuates Isoproterenol-Induced Cardiac Remodeling and Myocardial Infarction Injury in Rats

CGEN-856S is a novel Mas agonist. Herein, we examined the effects of this peptide on isoproterenol (ISO)-induced cardiac remodeling and myocardial infarction (MI) injury. We also sought to determine whether CGEN-856S activates the underlying mechanisms related to Mas receptor activation. Heart hyper...

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Bibliographic Details
Main Authors: Savergnini, Sílvia Q., Ianzer, Danielle, Carvalho, Mariana B. L., Ferreira, Anderson J., Silva, Gerluza A. B., Marques, Fúlvia D., Peluso, Antônio Augusto B., Beiman, Merav, Cojocaru, Gady, Cohen, Yossi, Almeida, Alvair P., Rotman, Galit, Santos, Robson A. S.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585977/