Robustness and Backbone Motif of a Cancer Network Regulated by miR-17-92 Cluster during the G1/S Transition

Robustness and Backbone Motif of a Cancer Network Regulated by miR-17-92 Cluster during the G1/S Transition

Based on interactions among transcription factors, oncogenes, tumor suppressors and microRNAs, a Boolean model of cancer network regulated by miR-17-92 cluster is constructed, and the network is associated with the control of G1/S transition in the mammalian cell cycle. The robustness properties of...

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Bibliographic Details
Main Authors: Yang, Lijian, Meng, Yan, Bao, Chun, Liu, Wangheng, Ma, Chengzhang, Li, Anbang, Xuan, Zhan, Shan, Ge, Jia, Ya
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585929/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585929/

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