An Entropic Mechanism of Generating Selective Ion Binding in Macromolecules

Several mechanisms have been proposed to explain how ion channels and transporters distinguish between similar ions, a process crucial for maintaining proper cell function. Of these, three can be broadly classed as mechanisms involving specific positional constraints on the ion coordinating ligands...

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Bibliographic Details
Main Authors: Thomas, Michael, Jayatilaka, Dylan, Corry, Ben
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585399/