Indoleamine-2,3-dioxygenase, an immunosuppressive enzyme that inhibits natural killer cell function, as a useful target for ovarian cancer therapy

Indoleamine-2,3-dioxygenase, an immunosuppressive enzyme that inhibits natural killer cell function, as a useful target for ovarian cancer therapy

This study examined the role of the immunosuppressive enzyme indoleamine-2,3-dioxygenase (IDO) in ovarian cancer progression, and the possible application of this enzyme as a target for ovarian cancer therapy. We transfected a short hairpin RNA vector targeting IDO into the human ovarian cancer cell...

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Bibliographic Details
Main Authors: WANG, DONGDONG, SAGA, YASUSHI, MIZUKAMI, HIROAKI, SATO, NAOTO, NONAKA, HIROAKI, FUJIWARA, HIROYUKI, TAKEI, YUJI, MACHIDA, SHIZUO, TAKIKAWA, OSAMU, OZAWA, KEIYA, SUZUKI, MITSUAKI
Format: Online
Language:English
Published: D.A. Spandidos 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584823/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584823/

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