Expression of Osteoprotegerin from a Replicating Adenovirus Inhibits the Progression of Prostate Cancer Bone Metastases in a Murine Model

Metastatic involvement of the skeleton is a frequent consequence of advanced prostate cancer. These skeletal metastases cause a number of debilitating complications and are refractory to current treatments. New therapeutic options are being explored, including conditionally replicating adenoviruses...

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Bibliographic Details
Main Authors: Cody, James J., Rivera, Angel A., Lyons, Gray R., Yang, Sherry W., Wang, Ming, Ashley, Jason W., Meleth, Sreelatha, Feng, Xu, Siegal, Gene P., Douglas, Joanne T.
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584184/