Biogenesis of RNA Polymerases II and III Requires the Conserved GPN Small GTPases in Saccharomyces cerevisiae

The GPN proteins are a poorly characterized and deeply evolutionarily conserved family of three paralogous small GTPases, Gpn1, 2, and 3. The founding member, GPN1/NPA3/XAB1, is proposed to function in nuclear import of RNA polymerase II along with a recently described protein called Iwr1. Here we s...

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Bibliographic Details
Main Authors: Minaker, Sean W., Filiatrault, Megan C., Ben-Aroya, Shay, Hieter, Philip, Stirling, Peter C.
Format: Online
Language:English
Published: Genetics Society of America 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584002/