The effects of cyclooxygenase-2 gene silencing by siRNA on cell proliferation, cell apoptosis, cell cycle and tumorigenicity of Capan-2 human pancreatic cancer cells

The prognosis of pancreatic cancer is still very poor. No specific effective gene therapy for pancreatic cancer has been found. As a key enzyme of the metabolic process of arachidonic acid, cyclooxygenase-2 (COX-2) has been found to be closely related to the tumorigenesis of epithelial cancers. Howe...

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Bibliographic Details
Main Authors: ZHONG, YINGQIANG, XIA, ZHONGSHENG, LIU, JUAN, LIN, YING, ZAN, HUI
Format: Online
Language:English
Published: D.A. Spandidos 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583541/