Silencing of the hTERT gene through RNA interference induces apoptosis via Bax/Bcl-2 in human glioma cells
Glioma cells are characterized by their invasiveness and resistance to conventional therapeutics. The downregulation of human telomerase reverse transcriptase (hTERT) can lead to decreased cell proliferation and/or the induction of apoptotic cell death in cancer cells but has rarely been reported in...
| Main Authors: | , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
D.A. Spandidos
2012
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583528/ |