Demethylation restores SN38 sensitivity in cells with acquired resistance to SN38 derived from human cervical squamous cancer cells

Demethylation restores SN38 sensitivity in cells with acquired resistance to SN38 derived from human cervical squamous cancer cells

Using seven monoclonal SN38-resistant subclones established from ME180 human cervical squamous cell carcinoma cells, we examined the demethylation effects of 5-aza-2′-deoxycytidine (5-aza-CdR) on the SN38-sensitivity of the cells as well as the expression of death-associated protein kinase (DAPK) in...

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Bibliographic Details
Main Authors: TANAKA, TETSUJI, BAI, TAO, TOUJIMA, SAORI, UTSUNOMIYA, TOMOKO, MATSUOKA, TOSHIHIDE, KOBAYASHI, AYA, YAMAMOTO, MADOKA, SASAKI, NORIYUKI, TANIZAKI, YUKO, UTSUNOMIYA, HIROTOSHI, TANAKA, JUNKO, YUKAWA, KAZUNORI
Format: Online
Language:English
Published: D.A. Spandidos 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583479/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583479/

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