tmRNA Is Essential in Shigella flexneri

Nonstop mRNAs pose a challenge for bacteria, because translation cannot terminate efficiently without a stop codon. The trans-translation pathway resolves nonstop translation complexes by removing the nonstop mRNA, the incomplete protein, and the stalled ribosome. P1 co-transduction experiments demo...

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Bibliographic Details
Main Authors: Ramadoss, Nitya S., Zhou, Xin, Keiler, Kenneth C.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581467/