Baicalein Triggers Mitochondria-Mediated Apoptosis and Enhances the Antileukemic Effect of Vincristine in Childhood Acute Lymphoblastic Leukemia CCRF-CEM Cells

Acute lymphoblastic leukemia (ALL) accounts for approximately 75% of childhood leukemia, and chemotherapy remains the mainstay therapy. Baicalein is an active flavonoid used in traditional Chinese medicine and has recently been found to have anticancer, anti-inflammatory, and antiallergic properties...

Full description

Bibliographic Details
Main Authors: Chen, Yun-Ju, Wu, Chieh-Shan, Shieh, Jeng-Jer, Wu, Jyh-Horng, Chen, Hsing-Yu, Chung, Ting-Wen, Chen, Yu-Kuo, Lin, Chi-Chen
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580913/