A rapidly progressing lymphocyte exhaustion after severe sepsis

Septic syndromes induce immune alterations that have long been considered solely an overwhelming pro-inflammatory response. Increasing evidence now suggests that, after the first pro-inflammatory hours, sepsis is accompanied by the occurrence of a systemic immune failure. Here, novel perspectives re...

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Bibliographic Details
Main Authors: Monneret, Guillaume, Venet, Fabienne
Format: Online
Language:English
Published: BioMed Central 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580699/