Does a prion-like mechanism play a major role in the apparent spread of α-synuclein pathology?
Parkinson's disease, the most common movement disorder, results in an insidious reduction for patients in quality of life and ability to function. A hallmark of Parkinson's disease is the brain accumulation of neuronal cytoplasmic inclusions comprised of the protein α-synuclein. The presen...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580457/ |