Armless mitochondrial tRNAs in Enoplea (Nematoda)

The mitochondrial genome of metazoan animal typically encodes 22 tRNAs. Nematode mt-tRNAs normally lack the T-stem and instead feature a replacement loop. In the class Enoplea, putative mt-tRNAs that are even further reduced have been predicted to lack both the T- and the D-arm. Here we investigate...

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Main Authors:	Jühling, Frank, Pütz, Joern, Florentz, Catherine, Stadler, Peter F.
Format:	Online
Language:	English
Published:	Landes Bioscience 2012
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579883/

id	pubmed-3579883
recordtype	oai_dc
spelling	pubmed-35798832013-02-27 Armless mitochondrial tRNAs in Enoplea (Nematoda) Jühling, Frank Pütz, Joern Florentz, Catherine Stadler, Peter F. RNA Families The mitochondrial genome of metazoan animal typically encodes 22 tRNAs. Nematode mt-tRNAs normally lack the T-stem and instead feature a replacement loop. In the class Enoplea, putative mt-tRNAs that are even further reduced have been predicted to lack both the T- and the D-arm. Here we investigate these tRNA candidates in detail. Three lines of computational evidence support that they are indeed minimal functional mt-tRNAs: (1) the high level of conservation of both sequence and secondary structure, (2) the perfect preservation of the anticodons, and (3) the persistence of these sequence elements throughout several genome rearrangements that place them between different flanking genes. Landes Bioscience 2012-09-01 /pmc/articles/PMC3579883/ /pubmed/23018779 http://dx.doi.org/10.4161/rna.21630 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Jühling, Frank Pütz, Joern Florentz, Catherine Stadler, Peter F.
spellingShingle	Jühling, Frank Pütz, Joern Florentz, Catherine Stadler, Peter F. Armless mitochondrial tRNAs in Enoplea (Nematoda)
author_facet	Jühling, Frank Pütz, Joern Florentz, Catherine Stadler, Peter F.
author_sort	Jühling, Frank
title	Armless mitochondrial tRNAs in Enoplea (Nematoda)
title_short	Armless mitochondrial tRNAs in Enoplea (Nematoda)
title_full	Armless mitochondrial tRNAs in Enoplea (Nematoda)
title_fullStr	Armless mitochondrial tRNAs in Enoplea (Nematoda)
title_full_unstemmed	Armless mitochondrial tRNAs in Enoplea (Nematoda)
title_sort	armless mitochondrial trnas in enoplea (nematoda)
description	The mitochondrial genome of metazoan animal typically encodes 22 tRNAs. Nematode mt-tRNAs normally lack the T-stem and instead feature a replacement loop. In the class Enoplea, putative mt-tRNAs that are even further reduced have been predicted to lack both the T- and the D-arm. Here we investigate these tRNA candidates in detail. Three lines of computational evidence support that they are indeed minimal functional mt-tRNAs: (1) the high level of conservation of both sequence and secondary structure, (2) the perfect preservation of the anticodons, and (3) the persistence of these sequence elements throughout several genome rearrangements that place them between different flanking genes.
publisher	Landes Bioscience
publishDate	2012
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579883/
_version_	1611956873163964416

Armless mitochondrial tRNAs in Enoplea (Nematoda)

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