High-density sub-100-nm peptide-gold nanoparticle complexes improve vaccine presentation by dendritic cells in vitro

Nanocarriers have been explored to improve the delivery of tumor antigens to dendritic cells (DCs). Gold nanoparticles are attractive nanocarriers because they are inert, non-toxic, and can be readily endocytosed by DCs. Here, we designed novel gold-based nanovaccines (AuNVs) using a simple self-ass...

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Bibliographic Details
Main Authors: Lin, Adam Yuh, Lunsford, Jessica, Bear, Adham Sean, Young, Joseph Keith, Eckels, Phillip, Luo, Laureen, Foster, Aaron Edward, Drezek, Rebekah Anna
Format: Online
Language:English
Published: Springer 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579702/