Circulating and Tumor-Infiltrating Myeloid-Derived Suppressor Cells in Patients with Colorectal Carcinoma

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous family of myeloid cells that suppress T cell immunity in tumor-bearing hosts. In patients with colon cancer, MDSCs have recently been described as Lin−/lowHLA-DR−CD11b+CD33+ cells correlating with cancer stage, metastasis and chemotherapy...

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Bibliographic Details
Main Authors: Zhang, Bin, Wang, Zhijun, Wu, Liangliang, Zhang, Meng, Li, Wei, Ding, Jianhua, Zhu, Jun, Wei, Huafeng, Zhao, Ke
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577767/