The Presence of Methylation Quantitative Trait Loci Indicates a Direct Genetic Influence on the Level of DNA Methylation in Adipose Tissue

The Presence of Methylation Quantitative Trait Loci Indicates a Direct Genetic Influence on the Level of DNA Methylation in Adipose Tissue

Genetic variants that associate with DNA methylation at CpG sites (methylation quantitative trait loci, meQTLs) offer a potential biological mechanism of action for disease associated SNPs. We investigated whether meQTLs exist in abdominal subcutaneous adipose tissue (SAT) and if CpG methylation ass...

Full description

Bibliographic Details
Main Authors: Drong, Alexander W., Nicholson, George, Hedman, Åsa K., Meduri, Eshwar, Grundberg, Elin, Small, Kerrin S., Shin, So-Youn, Bell, Jordana T., Karpe, Fredrik, Soranzo, Nicole, Spector, Tim D., McCarthy, Mark I., Deloukas, Panos, Rantalainen, Mattias, Lindgren, Cecilia M.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576415/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576415/

Similar Items